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Funded Project Details - FY2021

Project Number:

Title: Targeting the sphingosine-1-phosphate system in a mouse model of Gulf War Veterans' Illness
Principal Investigator:

Alpaslan Dedeoglu

Location: Boston, MA
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2020 - December 2021
FY 2021 Funding Amount: $268,736
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The pathophysiology of Gulf War Veterans’ Illness (GWVI) remains poorly understood, and treatments are lack- ing. Neurological symptoms including cognitive impairment, attention deficits, depression, and anxiety are a top complaint among GWVI patients. GWVI may be the result of exposure to drugs designed to protect military personnel from a chemical attack and from insects. These include: 1) pyridostigmine bromide (PB), 2) permethrin (PER), and 3) diethyltoluamide (DEET). Although these drugs ar...

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