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Project Number: | I01RX001776-05 |
| Title: | Traumatic Brain Injury and Endogenous Pain Modulation |
| Principal Investigator: | David J. Clark |
| Location: | Palo Alto, CA |
| Congressional District Code: | 18 |
| Research Service: | Rehabilitation R&D |
| Project Period: | April 2020 - March 2026 |
| FY 2021 Funding Amount: | $80,208 |
| Total Award Amount (all years): |
$1,150,785 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Chronic pain and disability after war-related injuries and after trauma sustained in civilian settings are unexpectedly common. Chronic pain related to traumatic brain injury (TBI) in combination with peripheral injuries is particularly problematic, and we have no well-validated treatments. Potentially explaining the TBI- chronic pain relationship, data from both humans and animal models suggest that descending pain modulation is disrupted after TBI. Recently collected data using laboratory mode... |