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Funded Project Details - FY2021




Project Number:

I01RX001475-06A1
Title: Autonomic Regulation of the Immunological Response to Limb Injury
Principal Investigator:

David J. Clark

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Rehabilitation R&D
Project Period: August 2020 - July 2025
FY 2021 Funding Amount: $124,000
Total Award Amount
(all years):
$1,184,704
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

A major recent advancement for the field of pain research is the recognition of immune system dysregulation as a contributor to the most serious adverse outcomes from injury. Both autoinflammation involving mediators of inflammation and autoimmunity involving autoantibodies have been identified in patients with chronic pain and disability after limb trauma. Taking advantage of these advancements, the overarching goal of the proposed research is to identify novel approaches to controlling immune...



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