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Funded Project Details - FY2021




Project Number:

I01RX003415-01
Title: Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Principal Investigator:

William A. Bauman

Location: Bronx, NY
Congressional District Code: 13
Research Service: Rehabilitation R&D
Project Period: June 2020 - May 2024
FY 2021 Funding Amount: $273,622
Total Award Amount
(all years):
$1,042,636
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Persons with chronic spinal cord injury (SCI) have markedly reduced bone mass and the loss of skeletal architectural integrity, which predisposes them to low-impact fractures. Currently, there is no practical treatment to reverse the severe bone loss in persons with chronic SCI. In the proposed study, a dual pharmacological intervention will be tested to improve bone health. Restoration of bone mass below the level of injury would be expected to reduce the morbidity associated with fractures and...



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