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Funded Project Details - FY2021

Project Number:

Title: Cause-specific Mortality among Users of Proton Pump Inhibitor
Principal Investigator:

Ziyad AlAly

Location: St Louis, MO
Congressional District Code: 1
Research Service: Health Services R&D
Project Period: April 2020 - March 2021
FY 2021 Funding Amount: $50,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Background: Proton Pump Inhibitors (PPI) are among the most commonly prescribed medications at the VA and elsewhere. Evidence suggests PPI use is associated with increased risk of adverse health outcomes including cardiovascular disease, pneumonia, Clostridium difficile infections, gastric cancer, and kidney disease. Recent studies suggested that PPI use is associated with increased risk of all-cause-mortality. Significance/Impact: These findings generated widespread concern among VA and outside...

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