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Funded Project Details - FY2021




Project Number:

I01BX000638-09A1
Title: Pathogenesis of Nerve Injury: Role of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1)
Principal Investigator:

Veronica I. Shubayev

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $340,613
Total Award Amount
(all years):
$1,606,655
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Extremity trauma causing peripheral nervous system (PNS) injury accounts for the majority of combat wounds. Despite high regenerative capacity of the PNS, patients develop severe neuropathic pain, not amenable to analgesic therapies. The congressional Opioids and STOP Initiative Act of 2017 calls to “expand, intensify, and coordinate fundamental, translational, and clinical research” on pain and develop new non-addictive pain treatments. In addition to physical and emotional disability, chronic...



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