Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021

Project Number:

Title: Pathogenesis of Nerve Injury: Role of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1)
Principal Investigator:

Veronica I. Shubayev

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2024
FY 2021 Funding Amount: $340,613
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Extremity trauma causing peripheral nervous system (PNS) injury accounts for the majority of combat wounds. Despite high regenerative capacity of the PNS, patients develop severe neuropathic pain, not amenable to analgesic therapies. The congressional Opioids and STOP Initiative Act of 2017 calls to “expand, intensify, and coordinate fundamental, translational, and clinical research” on pain and develop new non-addictive pain treatments. In addition to physical and emotional disability, chronic...

Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.