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Funded Project Details - FY2021

Project Number:

Title: Mechanisms that impact metastatic progression of triple negative breast cancer
Principal Investigator:

Rajeev S Samant

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2021 - December 2024
FY 2021 Funding Amount: $224,730
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


There is a notably high incidence of breast cancer among younger military women (20% to 40% higher). The incident rate of breast cancer for active duty women is seven times higher than the average incident rate of fifteen other cancer types across all service members. An estimated 90% of deaths due to breast cancer are a consequence of metastatic disease. Thus, metastasis is a formidable and clearly an unmet challenge. We identified that NMI (N-Myc Interactor) protein is undetectable in more tha...

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