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Funded Project Details - FY2021




Project Number:

I01BX004904-01A1
Title: Mitochondrial metabolism as a target of breast cancer therapy
Principal Investigator:

Antonino Passaniti

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: July 2020 - June 2024
FY 2021 Funding Amount: $278,841
Total Award Amount
(all years):
$1,320,205
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Significance – Breast cancer (BC) is one of the most common causes of cancer deaths for women with increasing incidence among women Veterans in the VA Health Care System. Patient survival has improved dramatically for primary BC but metastatic BC, for which targeted agents are usually not available, is common in African-American Veterans and is largely incurable. Most BC treatments target proliferating tumor cells that rely on glycolysis to fuel their metabolic needs. However, metastatic BC may...



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