Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021

Project Number:

Title: Mitochondrial metabolism as a target of breast cancer therapy
Principal Investigator:

Antonino Passaniti

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: July 2020 - June 2024
FY 2021 Funding Amount: $278,841
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Significance – Breast cancer (BC) is one of the most common causes of cancer deaths for women with increasing incidence among women Veterans in the VA Health Care System. Patient survival has improved dramatically for primary BC but metastatic BC, for which targeted agents are usually not available, is common in African-American Veterans and is largely incurable. Most BC treatments target proliferating tumor cells that rely on glycolysis to fuel their metabolic needs. However, metastatic BC may...

Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.