Office of Research & Development |
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Project Number: | I01BX003250-05 |
Title: | Regulation of pancreatitis severity |
Principal Investigator: | Fred S. Gorelick |
Location: | West Haven, CT |
Congressional District Code: | 3 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2020 - September 2024 |
FY 2021 Funding Amount: | $186,942 |
Total Award Amount (all years): |
$631,981 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: This proposal will continue the topic of our current Merit Award and examine a relatively recently described secretory protein, renalase, which appears to have a potent and novel protective role in acute pancreatitis (AP). AP has an incidence of up to 5/10,000 in the U.S. population, but is much more common in Veterans. It can cause death in 30% of those with severe disease, and is the most common reason for hospitalization for individuals with gastrointestinal disease in the U.S. Since AP is of... |