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Funded Project Details - FY2021

Project Number:

Title: Regulation of pancreatitis severity
Principal Investigator:

Fred S. Gorelick

Location: West Haven, CT
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $186,942
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


This proposal will continue the topic of our current Merit Award and examine a relatively recently described secretory protein, renalase, which appears to have a potent and novel protective role in acute pancreatitis (AP). AP has an incidence of up to 5/10,000 in the U.S. population, but is much more common in Veterans. It can cause death in 30% of those with severe disease, and is the most common reason for hospitalization for individuals with gastrointestinal disease in the U.S. Since AP is of...

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