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Funded Project Details - FY2021

Project Number:

Title: Host factors affecting susceptibility to Candida auris.
Principal Investigator:

Amy Hise

Location: Cleveland, OH
Congressional District Code: 11
Research Service: Biomedical Laboratory R&D
Project Period: January 2021 - December 2024
FY 2021 Funding Amount: $167,600
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


This VA Merit research project aims to define host factors associated with mucosal infection by an emerging multi-drug resistant human fungal pathogen, Candida auris. Most human fungal infections are caused by Candida spp, the most common being C. albicans which colonizes approximately half of healthy adults. Pathological overgrowth can occur with perturbations to the commensal microbiota or host immunity and is normally limited to mucosal surfaces. However, bloodstream infections due to Candida...

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