Validation of a novel animal model of post-traumatic epilepsy
Congressional District Code:
Biomedical Laboratory R&D
July 2020 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
PTE (posttraumatic epilepsy) has been identified by the VA as a priority area for research. Current medical therapy for this condition is inadequate. No anticonvulsant has yet been demonstrated to be specifically effective against PTE. The animal model used for screening anticonvulsants (AEDs) greatly influences which compounds are identified. One consequence is that standard animal models seem to consistently identify compounds with similar actions. Since there is no good PTE animal model, AEDs...