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Funded Project Details - FY2021




Project Number:

I01BX004870-01A1
Title: microRNA Regulation of The Cocaine Effects on the Cardiovascular System
Principal Investigator:

Chunming Dong

Location: Miami, FL
Congressional District Code: 24
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $185,748
Total Award Amount
(all years):
$688,948
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Despite the opioid overdose crisis, cocaine remains a widely abused illicit drug by the public and by veterans. While opioid overdose primarily causes respiratory failure, cocaine abuse is mainly associated with cardiovascular (CV) toxicities, which include hypertension (HTN), aortic stiffness, and atherosclerosis. Indeed, cocaine abuse represents a significant CV risk for the general population and for veterans. It is known that cocaine stimulates the sympathetic nervous system (SNS) by inhibit...



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