Funded Project Details - FY2021
|Title:|| CMA: Cartilage Repair Strategies to Alleviate Arthritic Pain (CaRe AP): Novel cell-based therapies to increase functional outcomes and alleviate pain in preclinical models of osteoarthritis|
Hicham M Drissi
|Congressional District Code:
||Biomedical Laboratory R&D
|| October 2020 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Overall Research Strategy: The overall goal of the CaRa-AP Collaborative Program is to develop a treatment for post-traumatic osteoarthritis (PTOA) that will relieve pain and improve function. We hypothesize that PTOA is caused by maladaptive repair responses including activation of the pro-inflammatory pathways of innate immunity that in turn result in pain, loss of function and structural decline. This Program addresses the hypothesis through two highly-integrated aims: (1) innovative intra-ar...
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