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Funded Project Details - FY2021

Project Number:

Title: CMA: Cartilage Repair Strategies to Alleviate Arthritic Pain (CaRe AP): Novel cell-based therapies to increase functional outcomes and alleviate pain in preclinical models of osteoarthritis
Principal Investigator:

Hicham M Drissi

Location: Decatur, GA
Congressional District Code: 4
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $288,908
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Overall Research Strategy: The overall goal of the CaRa-AP Collaborative Program is to develop a treatment for post-traumatic osteoarthritis (PTOA) that will relieve pain and improve function. We hypothesize that PTOA is caused by maladaptive repair responses including activation of the pro-inflammatory pathways of innate immunity that in turn result in pain, loss of function and structural decline. This Program addresses the hypothesis through two highly-integrated aims: (1) innovative intra-ar...

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