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Funded Project Details - FY2021

Project Number:

Title: The Role of Epigenetics in Mitochondrial Biogenesis-Mediated Recovery after Spinal Cord Injury
Principal Investigator:

Natalie E Scholpa

Location: Tucson, AZ
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: August 2020 - July 2025
FY 2021 Funding Amount: $203,250
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The goal of this project is to determine the role of epigenetic modifications of mitochondrial genes in the induction of the plateau phase after spinal cord injury (SCI), and to exploit these modifications to promote recovery. SCI is a devastating disorder often resulting in loss of function below the injury site. In recent years, service members have been threatened by more advanced warfare, such as improvised explosive devices, ultimately inducing more severe and complex injuries, including SC...

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