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Funded Project Details - FY2021

Project Number:

Title: BLRD Senior Research Career Scientist Renewal Application
Principal Investigator:

Jerome M. Siegel

Location: Sepulveda, CA
Congressional District Code: 33
Research Service: Biomedical Laboratory R&D
Project Period: April 2020 - March 2027
FY 2021 Funding Amount: $191,478
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Project Summary/Abstract: Role of hypocretin in opiate addiction and withdrawal Major causes of the opiate crisis are the addictive nature of opiates and the negative physiological and psychological effects of withdrawal that lead to relapse. These effects persist for months or years after the last dose is taken. In recent work we have found what may be the largest change in neuronal morphology in the brain of human heroin addicts; an average 54% increase in the number of neurons producing detec...

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