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Funded Project Details - FY2021




Project Number:

I01CX001891-05A2
Title: Natural Killer Cell Subpopulations in COPD Exacerbations
Principal Investigator:

Michael T Borchers

Location: Cincinnati, OH
Congressional District Code: 1
Research Service: Clinical Science R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $274,188
Total Award Amount
(all years):
$971,098
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Despite decades of research, no effective therapies exist to circumvent the irreversible alterations in lung function associated with COPD. Further, complications of COPD arise from acute and chronic exacerbations that amplify ongoing injury and remodeling that increase morbidity and mortality. The pathophysiology of exacerbations is poorly understood, but is primarily due to inflammation from infections. Some patients are more susceptible to exacerbations and represent an `exacerbator phenotype...



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