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Project Number: | I01CX001968-01A1 |
| Title: | Treatment of Veterans with Heart Failure with Reduced Ejection Fraction with Probenecid |
| Principal Investigator: | Jack Rubinstein |
| Location: | Cincinnati, OH |
| Congressional District Code: | 1 |
| Research Service: | Clinical Science R&D |
| Project Period: | January 2021 - December 2025 |
| FY 2023 Funding Amount: | $616,743 |
| Total Award Amount (all years): |
$2,572,955 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Heart failure with reduced ejection fraction (HFrEF) is a common cause for admission within the Veterans Affairs (VA) Health Care System. It is associated with severe impairment of physical and mental health status, and carries a high 5-yr mortality rate of ~75%. Even though significant progress has been made in understanding its pathophysiology, currently, its management and treatment is based on therapeutic targeting of a limited number of receptors and pathways. Our team and others have made... |