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Funded Project Details - FY2021

Project Number:

Title: Repeated Ketamine Treatment to Accelerate Efficacy of Prolonged Exposure in PTSD
Principal Investigator:

Paulo R Shiroma

Location: Minneapolis, MN
Congressional District Code: 5
Research Service: Clinical Science R&D
Project Period: January 2021 - December 2024
FY 2021 Funding Amount: $232,091
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Only sertraline and paroxetine are currently FDA‐approved to treat PTSD. Other psychotropics are equally limited to provide optimal respond. This efficacy gap may be particularly great in VA settings. The 2017 VA/DoD Clinical Practice Guideline for The Management of PTSD and Acute Stress Disorder recommends individual, manualized trauma-focused such as Prolonged Exposure (PE) over other pharmacologic interventions for the primary treatment of PTSD. However, a recent review of clinical trials of...

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