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Funded Project Details - FY2021




Project Number:

I01RX003363-01A1
Title: Targeting Schwann cell exosomes for treating neuropathic pain
Principal Investigator:

Wendy M. Campana

Location: San Diego, CA
Congressional District Code: 52
Research Service: Rehabilitation R&D
Project Period: October 2020 - September 2024
FY 2021 Funding Amount: $300,000
Total Award Amount
(all years):
$1,200,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

It is increasingly evident that Schwann cells (SCs) in the peripheral nervous system (PNS) function as a unit with neurons to regulate sensory function. When the PNS is injured in trauma, SCs become activated for repair. This involves dramatic phenotypic transformation. If this process is abnormal or inhibited, peripheral nerve injury can result in chronic debilitating pain, a problem observed in the general population, including numerous Veterans. Currently available treatment options for chron...



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