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Funded Project Details - FY2021

Project Number:

Title: Optimizing Delivery of a Known Therapeutic Agent, Dexamethasone, to Improve Microelectrode Recording Performance
Principal Investigator:

Andrew Shoffstall

Location: Cleveland, OH
Congressional District Code: 11
Research Service: Rehabilitation R&D
Project Period: August 2020 - July 2024
FY 2021 Funding Amount: $288,555
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The overall goal of this proposal is to improve the chronic performance of intracortical recording microelectrodes using a targeted drug-delivery approach. Microelectrode-based devices have the potential to resolve many challenges in rehabilitation for Veterans with paralysis and/or amputation. Notably, brain-computer interface (BCI) endeavors within the VA have provided patients the ability to control electromechanical or neuromuscular prostheses using ‘thoughts’ or signals from their motor cor...

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