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Funded Project Details - FY2021




Project Number:

IK2RX003407-01A1
Title: Retinal microvasculature as a predictor of neurodegeneration in multiple sclerosis
Principal Investigator:

Elizabeth Silbermann

Location: Portland, OR
Congressional District Code: 3
Research Service: Rehabilitation R&D
Project Period: October 2020 - September 2025
FY 2021 Funding Amount: $356,196
Total Award Amount
(all years):
$1,928,786
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Objectives: Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative illness that affects nearly 1 million people in the United States. Currently, there are no FDA-approved treatments that directly address neurodegeneration and its associated clinical impairment. Systemic vascular disease comorbidities, including hypertension, hyperlipidemia, and obesity, independently worsen MS-related walking limitations. In addition, MS pathology demonstrates microvascular dysfunction in the ce...



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