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Project Number: | IK2RX003407-01A1 |
| Title: | Retinal microvasculature as a predictor of neurodegeneration in multiple sclerosis |
| Principal Investigator: | Elizabeth Silbermann |
| Location: | Portland, OR |
| Congressional District Code: | 3 |
| Research Service: | Rehabilitation R&D |
| Project Period: | October 2020 - September 2025 |
| FY 2021 Funding Amount: | $356,196 |
| Total Award Amount (all years): |
$1,928,786 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Objectives: Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative illness that affects nearly 1 million people in the United States. Currently, there are no FDA-approved treatments that directly address neurodegeneration and its associated clinical impairment. Systemic vascular disease comorbidities, including hypertension, hyperlipidemia, and obesity, independently worsen MS-related walking limitations. In addition, MS pathology demonstrates microvascular dysfunction in the ce... |