Office of Research & Development |
![]() ![]() |
Project Number: | I21RX003581-01 |
Title: | Effects of Acute Exercise on Functional Magnetic Resonance Spectroscopy Measures of GABA in Aging and Chronic Stroke |
Principal Investigator: | Keith McGregor |
Location: | Decatur, GA |
Congressional District Code: | 4 |
Research Service: | Rehabilitation R&D |
Project Period: | January 2021 - December 2022 |
FY 2021 Funding Amount: | $74,818 |
Total Award Amount (all years): |
$199,676 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The current proposal seeks to index the effect of acute aerobic exercise on excitatory and inhibitory balance using magnetic resonance spectroscopy (MRS) in aging and in chronic stroke. There exists replicated evidence that acute bouts of aerobic exercise increase sensorimotor gamma-aminobutyric acid (GABA) within a two-hour period. Our lab has the technical capability to reliably measure GABA between two sessions and we have developed a functional measure of motor learning that alters GABA in o... |