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Funded Project Details - FY2021

Project Number:

Title: Comparative Effectiveness and Safety of Newer and Older Antihyperglycemic Medications
Principal Investigator:

Ziyad AlAly

Location: St Louis, MO
Congressional District Code: 1
Research Service: Health Services R&D
Project Period: July 2021 - June 2025
FY 2021 Funding Amount: $73,314
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Background: People diagnosed with diabetes are initially advised on lifestyle changes and started on metformin, but often require the addition of 2nd line antihyperglycemic medications. The choice of 2nd line antihyperglycemic therapy is complex because the multiple available drugs, distributed across several drug classes, have different benefits and risks. Newer 2nd line antihyperglycemics (sodium-glucose co-transporter-2 inhibitor (SGLT2i), and glucagon-like peptide-1 receptor agonist (GLP1))...

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