Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021

Project Number:

Title: Assessment of cardiotoxicity in Immunity Checkpoint Blockers and other cancer therapies
Principal Investigator:

Mary S. Vaughan-Sarrazin

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Health Services R&D
Project Period: September 2020 - February 2022
FY 2021 Funding Amount: $128,691
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Background: Lung cancer is a leading cause of death from cancer death worldwide, and non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases. Advances in NSCLC treatment using tyrosine kinase inhibitors (TKI) and immunity checkpoint blockers (ICB) have led to improved survival. However, there is a growing concern that cardiotoxicity associated with novel cancer therapies may lead to premature morbidity among survivors. Unfortunately, heart damage due to cardiotoxicity is oft...

Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.