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Funded Project Details - FY2021




Project Number:

I21HX003116-01A1
Title: Assessment of cardiotoxicity in Immunity Checkpoint Blockers and other cancer therapies
Principal Investigator:

Mary S. Vaughan-Sarrazin

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Health Services R&D
Project Period: September 2020 - February 2022
FY 2021 Funding Amount: $128,691
Total Award Amount
(all years):
$200,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Background: Lung cancer is a leading cause of death from cancer death worldwide, and non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases. Advances in NSCLC treatment using tyrosine kinase inhibitors (TKI) and immunity checkpoint blockers (ICB) have led to improved survival. However, there is a growing concern that cardiotoxicity associated with novel cancer therapies may lead to premature morbidity among survivors. Unfortunately, heart damage due to cardiotoxicity is oft...



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