Funded Project Details - FY2021
|Title:|| A role and regulation of glucose responsive lipolysis in pancreatic beta cells|
||Iowa City, IA
|Congressional District Code:
||Biomedical Laboratory R&D
|| January 2021 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
T2D is a major health problem for US veterans that imposes significant physical, financial, and emotional tolls. Thus, there is a strong and urgent need for an effective and widely applicable therapy. Excessive accumulation of lipids in beta cells is considered to contribute to the development of T2D. Experimental data supports that lipid overload activates multiple stress pathways including inflammation, ER stress, oxidative stress, and mitochondrial dysfunction ultimately leading to the loss o...
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