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Funded Project Details - FY2021

Project Number:

Title: Urocortin 2 Gene Transfer for Heart Failure with Preserved Ejection Fraction
Principal Investigator:

H. Kirk Hammond

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $123,366
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


This proposal focuses on development of a new treatment for patients with heart failure and preserved ejection fraction (HFpEF). Among symptomatic patients with HF, half have HFpEF, and their mortality is similar to those with HFrEF. However, there are currently no treatments for HFpEF that prolong life, and few (if any) that reliably reduce HF hospitalization rates. We need new therapies to address this unmet medical need. Cardiovascular gene transfer is conceptually an attractive method for tr...

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