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Funded Project Details - FY2021




Project Number:

I01BX003767-05
Title: Discovering Novel Mechanisms and Treatment for Aging-Related Dementia: Probing Medin and Abeta Vasculopathy
Principal Investigator:

Raymond Migrino

Location: Phoenix, AZ
Congressional District Code: 9
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - September 2025
FY 2021 Funding Amount: $82,362
Total Award Amount
(all years):
$710,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Abstract Vascular dementia (VaD) is the second most common cause of dementia overall and the most common in patients < 74 years old. In an aging veteran population, dementia is a critical health care issue that affects 7.3% of veterans ≥ 65 years old1. To prevent or manage VaD, it is critical to understand its early pathophysiology, specifically learning how vascular disease and inflammation, a process that occurs decades before VaD, modulate neuroinflammation and neurodegeneration. We have ide...



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