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Funded Project Details - FY2021

Project Number:

Title: The role of AMPK and CD36 in breast cancer tumorigenesis and metastasis
Principal Investigator:

Nissim Hay

Location: Chicago, IL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $132,500
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Breast cancer is the most frequently occurring cancer in women. Military women are at increased risk of breast cancer. The mortality and morbidity from breast cancer is due to its metastatic spread. The role of AMPK in tumorigenesis is controversial. Although AMPK inhibition was implicated in promoting tumorigenesis, we showed, several years ago, that AMPK activation is required for tumor cells survival during solid tumor formation. In recent years this assertion was independently corroborated b...

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