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Funded Project Details - FY2021

Project Number:

Title: Sex Chromosome Aneuploidies in Autoimmune Disease
Principal Investigator:

Robert H. Scofield

Location: Oklahoma City, OK
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: September 2021 - September 2025
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Abstract Systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS) are chronic, inflammatory, autoimmune diseases. Some features of these illnesses are similar. These include aspects of clinical manifestations, serology and epidemiology. Most critical for this proposal is that there is a strong female bias found for both diseases such that at least 90% of patients are women. The mechanism for this sex bias was unexplained until the work of the PI, which began more than a decade ago and was...

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