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Funded Project Details - FY2021

Project Number:

Title: Basic Mechanisms on Hearing Loss of Cochlear Origin
Principal Investigator:

Allen F. Ryan

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: January 2021 - December 2024
FY 2021 Funding Amount: $210,431
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Objectives: Sensorineural hearing loss (SNHL) is strongly associated with many aspects of military service including blast injury. The overall objectives of this proposal are to improve the prevention and treatment of SNHL in Veterans. Research Design: We previously used in vitro screening to identify novel compounds that can protect hair cells (HCs) from ototoxic damage. We tested them in vivo against noise-induced hearing loss (NIHL) and found partial protection. We also used high-resolution p...

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