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Funded Project Details - FY2021




Project Number:

I01BX005351-01
Title: The Role of PDEF in Prostate Cancer
Principal Investigator:

Hari Koul

Location: New Orleans, LA
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $174,295
Total Award Amount
(all years):
$1,160,932
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Project Summary: Prostate Cancer (PCa) accounts for ~30000 deaths annually in the USA. There is urgent, yet unmet, need for identification and characterization of new targets for therapeutic intervention in PCa. Our goal is to address this vital knowledge gap by characterizing the role of Prostate Derived Ets Transcription Factor (PDEF) in PCa, thereby reducing the prostate cancer-related deaths. Our central hypotheses are that, “PDEF suppresses CRPC phenotype and PCa metastasis in part by modul...



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