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Project Number: | I01BX005422-01 |
| Title: | COVID-19 Related Tissue Immunopathology |
| Principal Investigator: | Laura Su |
| Location: | Philadelphia, PA |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2021 - March 2023 |
| FY 2021 Funding Amount: | $78,400 |
| Total Award Amount (all years): |
$325,900 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary An ongoing outbreak of a novel coronavirus infection (COVID-19) has claimed hundreds of thousands of lives and disrupted social infrastructures around the world. Immunopathology from hyperactive host immune system contributes to the clinical severity of COVID-19. The proposed study will test the hypothesis that pathologic T cell and B cell interactions promote autoantibody production to mediate tissue damage in critically ill COVID-19 patients. In Aim 1, we will quantify the brea... |