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Funded Project Details - FY2021

Project Number:

Title: B-cell innate and adaptive protective immunity to SARS-CoV-2
Principal Investigator:

John D. Mountz

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: February 2021 - January 2023
FY 2021 Funding Amount: $103,850
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The COVID-19 caused by the SARS-CoV-2 coronavirus infection is currently a global pandemic. The most important question is why some individuals produce rapid protective antibodies (Abs) and exhibit null or only mild symptoms, whereas others do not? A second urgent question is if a standard laboratory test can be developed to stratify subjects who would be most likely to develop rapid long-lived B cells that could produce protective Abs after infection or after vaccination? Based on the understan...

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