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Funded Project Details - FY2021

Project Number:

Title: BLRD Merit Review Research Career Scientist (RCS) Award (IK6)
Principal Investigator:

Jin Chen

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: October 2020 - September 2027
FY 2021 Funding Amount: $149,213
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Project Summary/Abstract The goals of my research programs are to elucidate molecular mechanisms of tumor angiogenesis, cancer metabolism, and anti-tumor immunity, and to translate our discoveries towards improved cancer therapy. During this RCS award period I will continue to: (1) Targeting mTOR signaling pathways in lung cancer subtypes that are refractory to current targeted therapies. We demonstrated previously that mTOR is a common signaling node downstream of “bypass” kinases, and targetin...

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