Funded Project Details - FY2021
|Title:|| Effect of Gut Microbiome Dysbiosis in the Pathobiology of Multiple Sclerosis|
||Iowa City, IA
|Congressional District Code:
||Clinical Science R&D
|| January 2021 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Despite the association between gut microbiota and multiple sclerosis (MS) being increasingly appreciated, the mechanism through which gut bacteria and their metabolites modulate disease in MS is poorly understood. We and others have shown a link between perturbations in the gut microbiota in MS patients. Gut dysbiosis, a qualitative alteration in healthy gut microbiota is characterized by an increased abundance of inflammation-promoting bacteria (pathobiont) and depletion of beneficial bacteria...
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