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Funded Project Details - FY2021

Project Number:

Title: Improving the Assessment of Myelin and Axonal Integrity in Early Multiple Sclerosis
Principal Investigator:

francesca r bagnato

Location: Nashville, TN
Congressional District Code: 5
Research Service: Clinical Science R&D
Project Period: July 2021 - June 2025
FY 2021 Funding Amount: $66,768
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


PROJECT SUMMARY Neurodegeneration, characterized by myelin and axonal injury, is a key driver in multiple sclerosis (MS) pathology and a major determinant of patients’ disability and outcome. Currently, it is not possible to assess neurodegeneration in vivo because there are no magnetic resonance imaging (MRI) biomarkers sensitive and specific to myelin and axonal injury. Finding this biometric is set as a major priority by an MS International Panel of Experts, as a path toward halting neurodeg...

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