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Funded Project Details - FY2021




Project Number:

I01RX003502-01A1
Title: Development of Poly (pro-curcumin) Polymer Coatings to Improve Cortical Electrode Biocompatibility
Principal Investigator:

Ryan Gilbert

Location: Albany, NY
Congressional District Code: 20
Research Service: Rehabilitation R&D
Project Period: February 2021 - January 2025
FY 2021 Funding Amount: $200,001
Total Award Amount
(all years):
$1,200,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

This application aims to create innovative polymer coatings to improve intracortical microelectrode biocompatibility. Following intracortical microelectrode implantation, an inflammatory response leads to neuronal loss and the formation of a glial scar around the implant. The loss of neurons and the formation of the glial scar lead to diminished recordings of nearby neurons over time. Biomaterial coatings have the potential of mitigating the inflammatory and glial scarring response. However, dru...



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