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Funded Project Details - FY2021




Project Number:

I01RX002691-01A2
Title: Mechanistic role of vascular dysfunction in TBI-mediated cognitive dysfunction
Principal Investigator:

Raymond Migrino

Location: Phoenix, AZ
Congressional District Code: 9
Research Service: Rehabilitation R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $180,878
Total Award Amount
(all years):
$1,200,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Abstract Mild traumatic brain injury (mTBI) is a major cause of mortality and morbidity especially among service- members and veterans. mTBI is linked to long-term development of dementia conditions such as Alzheimer's disease and related disorders, but the exact pathophysiologic mechanisms remain poorly-defined. Vascular disease and cardiovascular risk factors are strongly linked with dementia. We propose to test the hypothesis that long-term mTBI-induced cognitive dysfunction is due to, at le...



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