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Project Number: | I01RX002691-01A2 |
| Title: | Mechanistic role of vascular dysfunction in TBI-mediated cognitive dysfunction |
| Principal Investigator: | Raymond Migrino |
| Location: | Phoenix, AZ |
| Congressional District Code: | 9 |
| Research Service: | Rehabilitation R&D |
| Project Period: | April 2021 - March 2025 |
| FY 2021 Funding Amount: | $180,878 |
| Total Award Amount (all years): |
$1,200,000 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Abstract Mild traumatic brain injury (mTBI) is a major cause of mortality and morbidity especially among service- members and veterans. mTBI is linked to long-term development of dementia conditions such as Alzheimer's disease and related disorders, but the exact pathophysiologic mechanisms remain poorly-defined. Vascular disease and cardiovascular risk factors are strongly linked with dementia. We propose to test the hypothesis that long-term mTBI-induced cognitive dysfunction is due to, at le... |