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Funded Project Details - FY2021

Project Number:

Title: Protective pathways in sepsis-induced renal injury
Principal Investigator:

Takashi Hato

Location: Indianapolis, IN
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $128,400
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Project Summary/Abstract Sepsis-induced acute kidney injury is a major life-threatening condition with no effective therapy to date. The host responses to sepsis are wide-ranging, cell-type dependent, and importantly, temporally distinct. These cellular and molecular responses to sepsis can favorably or negatively affect host fitness. However, the distinction between adaptive and maladaptive responses is often not apparent a priori, and the same response may have opposite implications depending...

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