Funded Project Details - FY2021
|Title:|| Circadian Rhythms in Neuronal Models of Bipolar Disorder|
Michael J McCarthy
||San Diego, CA
|Congressional District Code:
||Biomedical Laboratory R&D
|| April 2021 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Bipolar disorder (BD) is a psychiatric disorder associated with heritable polygenic risk factors. While clinically heterogeneous, key clinical features of BD include disruptions in daily sleep and activity cycles indicating that circadian rhythm disruption is an important part of the disorder in many patients. Circadian rhythms are determined by molecular clocks comprised of “clock genes” whose expression is regulated by environmental factors such as light and temperature. In recent years, our g...
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