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Funded Project Details - FY2021




Project Number:

I01BX005322-01A1
Title: Remote injury responses after AKI
Principal Investigator:

Andreas Herrlich

Location: St Louis, MO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: July 2021 - June 2025
FY 2021 Funding Amount: $90,102
Total Award Amount
(all years):
$704,379
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

PROJECT SUMMARY ABSTRACT The overall goal of our research is to develop novel strategies to treat secondary complications of acute kidney injury (AKI). Remote acute lung injury (ALI) is a frequent and often lethal complication of acute kidney injury (AKI) that lacks therapies. Molecular mechanisms of AKI-ALI are incompletely understood, but circulating inflammatory cytokines, e.g. tumor-necrosis-factor (TNF) and T cells have been implicated. Which specific kidney cell types release and which lun...



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