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Funded Project Details - FY2021

Project Number:

Title: Remote injury responses after AKI
Principal Investigator:

Andreas Herrlich

Location: St Louis, MO
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: July 2021 - June 2025
FY 2021 Funding Amount: $90,102
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


PROJECT SUMMARY ABSTRACT The overall goal of our research is to develop novel strategies to treat secondary complications of acute kidney injury (AKI). Remote acute lung injury (ALI) is a frequent and often lethal complication of acute kidney injury (AKI) that lacks therapies. Molecular mechanisms of AKI-ALI are incompletely understood, but circulating inflammatory cytokines, e.g. tumor-necrosis-factor (TNF) and T cells have been implicated. Which specific kidney cell types release and which lun...

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