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Funded Project Details - FY2021

Project Number:

Title: Pharmachin Optimization and Testing
Principal Investigator:

Michael K. Riscoe

Location: Portland, OR
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: April 2021 - March 2025
FY 2021 Funding Amount: $109,621
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


We seek to develop a potent Pharmachin derivative with activity against blood forms of P. falciparum and P. vivax. It is our ultimate goal to develop an inexpensive anti-malarial that is safe for use in G6PD deficient individuals, and in the most vulnerable populations, i.e., pregnant women and children, and can be administered by oral and parenteral routes for weekly chemo-prevention as well as treatment of malaria, including severe malaria. Our 4-year goal for this VA Merit Review Award is to...

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