VA Research Currents archive
A win for the little guy: Study finds shorter men live longer
May 29, 2014
Shorter men are more likely to live longer than their towering counterparts. That's the consensus researchers came to following a more than 40-year study
of some 8,000 American men of Japanese ancestry.
The study was published in the May 7, 2014, issue of PLOS ONE.
The Honolulu Heart Program/Honolulu-Asia Aging Study followed the men, all of whom were born between 1900 and 1919 and were living in Oahu, Hawaii, in the
According to Dr. Qimei He, a VA researcher who worked on the study, shorter men not only lived longer, they had lower blood insulin levels and less cancer
"The taller you got, the shorter you lived," said lead author Dr. Bradley Willcox, of the University of Hawaii, in a news release from the school.
The researchers split the men into two groups, those 5 feet 2 inches and shorter, and those 5 feet 4 inches and taller.
Shorter men were more likely to have a protective form of the gene FOXO3, which is linked to longevity. The gene led to smaller body size during early
development and a longer lifespan.
The results fly in the face of the conventional notion that height in developed nations is directly correlated to nutrition, with healthier children
growing taller than those with poor nutrition. With that in mind, one might expect taller persons to have a lower mortality rate.
Not so, at least according to this study. Despite the study's firm conclusions, the authors acknowledge that the reasons for longevity are likely far more
complex than just which form of the FOX03 gene a person has.
"The study doesn't explain why we see a higher mortality rate in taller men," says He. "There are several possibilities, including diet and metabolism. For
example, there are some studies in animals that indicate longevity may be correlated with a relatively low-calorie diet during the growing period and
This does not mean that being tall means you have to die young or that being short is a recipe for long life, emphasizes He. "You can't control your
height, no matter how much you may want to, but you can control your diet. You can control your children's diets. You can exercise and make sure they
exercise. That is how you live longer."
Of the original 8,006 study participants, around 1,200 lived into their 90s. About 250 are still alive.